|
|
| |
| |
 |
Dr. Ivana MIHALEK
Principal Investigator
Details |
| |
| |
| Group Members |
| |
| Name | Title |
| Dr. Ivana Mihalek |
Principal Investigator |
| Dr. LI Qiang |
Postdoctoral Fellow |
| Ms. Zhang Zong Hong |
Research Associate |
|
| |
Research Overview
The aim of our group is to reverse engineer the function of a protein through studying its evolution. We use bioinformatics to get the first inkling of the layout and mechanism of these biological nanomachines, and computer simulation to test, to the extent it currently allows, the reasonableness of our interpretation of bioinformatics data. Ultimately, the goal is to build a straightforward hypothesis which can then be tested experimentally. Therefore we invest serious effort into developing ways to present our findings in the most useful and compact way to our experimentalist colleagues.
|
| |
| More Details |
| |
|
| |
| Selected Publications |
| |
- Mihalek I, Res I, Lichtarge O.
Background frequencies for residue variability estimates: BLOSUM revisited.
BMC Bioinformatics. 2007 Dec 27;8(1):488 [Epub ahead of print]
PMID: 18162129 [PubMed - as supplied by publisher]
|
|
|
