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  Biography Details
 
Dr. Vivek TANAVDE
Principal Investigator
 
Areas of Research Interest
 
  • Mesenchymal Stem Cells
  • Hematopoietic Stem Cells
  • Cell signaling in stem cells
 
Biography
 
Dr Vivek Tanavde joined the Bioinformatics Institute in 2006. Prior to that, he was heading the hematopoietic stem cell lab at Reliance Life Sciences, India. He obtained his Ph.D. in Applied Biology at the Cancer Research Institute in Mumbai. In 1999, he joined Dr. Curt Civin's lab at Johns Hopkins as a post doctoral fellow & worked on expansion of umbilical cord blood stem cells. He also holds adjunct appointment at the Department of Biological Sciences, National University of Singapore.
 
Selected Publications
 
  1. Ng F, Boucher S, Koh S, Sastry KS, Chase L, Lakshmipathy U, Choong C, Yang Z, Vemuri MC, Rao MS, Tanavde V.
    PDGF, TGF-b and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSC into adipogenic, chondrogenic and ostoegenic lineages.
    Blood. 2008 Mar 10; [Epub ahead of print]
    PMID: 18332228 [PubMed - as supplied by publisher]


  2. Shetty P, Bharucha K, Tanavde V.
    Human umbilical cord blood serum can replace fetal bovine serum in the culture of mesenchymal stem cells.
    Cell Biol Int. 2007 Mar;31(3):293-8. Epub 2006 Nov 19.
    PMID: 17208468 [PubMed - indexed for MEDLINE]


  3. Georgantas RW 3rd, Tanadve V, Malehorn M, Heimfeld S, Chen C, Carr L, Martinez-Murillo F, Riggins G, Kowalski J, Civin CI.
    Microarray and serial analysis of gene expression analyses identify known and novel transcripts overexpressed in hematopoietic stem cells.
    Cancer Res. 2004 Jul 1;64(13):4434-41.
    PMID: 15231652 [PubMed - indexed for MEDLINE]


  4. Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L.
    Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells.
    Mol Ther. 2003 Jun;7(6):827-38.
    PMID: 12788657 [PubMed - indexed for MEDLINE]


  5. Whartenby KA, Straley EE, Kim H, Racke F, Tanavde V, Gorski KS, Cheng L, Pardoll DM, Civin CI.
    Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation.
    Blood. 2002 Nov 1;100(9):3147-54.
    PMID: 12384412 [PubMed - indexed for MEDLINE]


  6. Tanavde VM, Malehorn MT, Lumkul R, Gao Z, Wingard J, Garrett ES, Civin CI.
    Human stem-progenitor cells from neonatal cord blood have greater hematopoietic expansion capacity than those from mobilized adult blood.
    Exp Hematol. 2002 Jul;30(7):816-23.
    PMID: 12135681 [PubMed - indexed for MEDLINE]
 

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