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Dr. Manfred KORANDA
Principal Investigator
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| Areas of Research Interest |
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- Signal Transduction and Transcriptional Regulation
- Parasite-Host Interactions
- Asymmetric Cell Division
- Molecular Mechanisms Underlying Obesity
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| Biography |
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| Manfred Koranda joined the Bioinformatics Institute A*STAR Singapore as a Principal Investigator in August 2007. He leads a biochemistry and molecular biology lab that aims to bridge the gap between theoretical predictions of proteins with unknown functions and their cellular biology, which can subsequently be used to aid the identification of novel drug targets. Prior to this appointment, he was a team leader of the biochemistry team within the Department of Bioinformatics at the Institute of Molecular Pathology (IMP) in Vienna, Austria, In close collaboration with the University of Vienna, he set up a biochemistry lab to validate bioinformatics predictions and focus on the biochemical properties and structure-function relationships of a variety of proteins. He obtained his MSc and PhD degrees at the University of Vienna (Austria), and worked as a postdoctoral scientist at the University of Dundee (Scotland, UK). |
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| Selected Publications |
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- Veis J, Klug H, Koranda M, Ammerer G.
Activation of the G2/M-specific gene CLB2 requires multiple cell cycle signals.
Mol Cell Biol. 2007 Dec;27(23):8364-73. Epub 2007 Oct 1.
PMID: 17908798 [PubMed - indexed for MEDLINE]
- Maurer-Stroh S, Koranda M, Benetka W, Schneider G, Sirota FL, Eisenhaber F.
Towards complete sets of farnesylated and geranylgeranylated proteins.
PloS Comput Biol. 2007 Apr 6;3(4):e66. Epub 2007 Feb 23.
PMID: 17411337 [PubMed - indexed for MEDLINE]
- Benetka W, Koranda M, Maurer-Stroh S, Pittner F, Eisenhaber F.
Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo.
BMC Biochem. 2006 Feb 28;7:6.
PMID: 16507103 [PubMed - indexed for MEDLINE]
- Koranda M, Schleiffer A, Endler L, Ammerer G.
Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters.
Nature. 2000 Jul 6;406(6791):94-8.
PMID: 10894549 [PubMed - indexed for MEDLINE]
- Doetzlhofer A, Rotheneder H, Lagger G, Koranda M, Kurtev V, Brosch G, Wintersberger E, Seiser C.
Histone deacetylase 1 can repress transcription by binding to Sp1.
Mol Cell Biol. 1999 Aug;19(8):5504-11.
PMID: 10409740 [PubMed - indexed for MEDLINE]
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Please contact us by email if you wish a reprint from any of the selected publications. |
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