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  Biography Details
 
Dr. Mallur Srivatsan MADHUSUDHAN
Principal Investigator
 
Areas of Research Interest
 
  • Predicting the composition, and modelling the 3D structures of biomolecular complexes
  • Protein structure modelling and functional annotation
  • Protein-ligand docking
 
Biography
 
Dr. M. S. Madhusudhan joined the Bioinformatics Institute as a Principal Investigator in 2008. He received a Masters degree in Physics from the University of Pune and a PhD in Biophysics from the Molecular Biophysics Unit, Indian Institute of Science. This was followed by post-doctoral work in the lab of Andrej Sali at the Rockefeller University and University of California, San Francisco.
 
Selected Publications
 
  1. Bajaj K, Madhusudhan MS, Adkar BV, Chakrabarti P, Ramakrishnan C, Sali A, Varadarajan R.
    Stereochemical criteria for prediction of the effects of proline mutations on protein stability.
    PLoS Comput Biol. 2007 Dec;3(12):e241.
    PMID: 18069886 [PubMed - indexed for MEDLINE]


  2. Davis FP, Braberg H, Shen MY, Pieper U, Sali A, Madhusudhan MS.
    Protein complex compositions predicted by structural similarity.
    Nucleic Acids Res. 2006 May 31;34(10):2943-52. Print 2006.
    PMID: 16738133 [PubMed - indexed for MEDLINE]


  3. Madhusudhan MS, Marti-Renom MA, Sanchez R, Sali A.
    Variable gap penalty for protein sequence-structure alignment.
    Protein Eng Des Sel. 2006 Mar;19(3):129-33. Epub 2006 Jan 19.
    PMID: 16423846 [PubMed - indexed for MEDLINE]


  4. M.S. Madhusudhan, M.A. Marti-Renom, N. Eswar, B. John, U. Pieper, R. Karchin, Min-yi Shen, A. Sali.
    Comparative Protein Structure Modeling.
    In: The Proteomics Protocols Handbook. Ed: J.M. Walker. Humana Press Inc., Totowa, NJ, 2005, 831-860.


  5. Marti-Renom MA, Madhusudhan MS, Sali A.
    Alignment of protein sequences by their profiles.
    Protein Sci. 2004 Apr;13(4):1071-87.
    PMID: 15044736 [PubMed - indexed for MEDLINE]


  6. Marti-Renom MA, Madhusudhan MS, Fiser A, Rost B, Sali A.
    Reliability of assessment of protein structure prediction methods.
    Structure. 2002 Mar;10(3):435-40.
    PMID: 12005441 [PubMed - indexed for MEDLINE]


  7. Madhusudhan MS, Vishveshwara S.
    Deducing hydration sites of a protein from molecular dynamics simulations.
    J Biomol Struct Dyn. 2001 Aug;19(1):105-14.
    PMID: 11565842 [PubMed - indexed for MEDLINE]


 

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