 |
| |
| |
| |
 |
Dr. Ivana MIHALEK
Principal Investigator
 |
| |
| Areas of Research Interest |
| |
- Understanding evolution of biological macromolecules and using that knowledge to understand their present day function
|
| |
| Biography |
| |
| Ivana Mihalek moved to Singapore in 2007. She obtained her undergraduate degree in physics from University of Zagreb, Zagreb, Croatia, and degrees in physics (PhD) and computer science (MS) from University of Kentucky, Lexington, Kentucky. In 2001 she started her work in bioinformatics as a postdoctoral researcher at Baylor College of Medicine, Houston, Texas. |
| |
| Selected Publications |
| |
- Mihalek I, Res I, Lichtarge O.
Background frequencies for residue variability estimates: BLOSUM revisited.
BMC Bioinformatics. 2007 Dec 27;8(1):488 [Epub ahead of print]
PMID: 18162129 [PubMed - as supplied by publisher]
- Item CB, Mihalek I, Lichtarge O, Jalan A, Vodopiutz J, Muhl A, Bodamer OA.
Manifestation of hawkinsinuria in a patient compound heterozygous for hawkinsinuria and tyrosinemia III.
Mol Genet Metab. 2007 Aug;91(4):379-83. Epub 2007 Jun 7.
PMID: 17560158 [PubMed - indexed for MEDLINE]
- Mihalek I, Res I, Lichtarge O.
On itinerant water molecules and detectability of protein-protein interfaces through comparative analysis of homologues.
J Mol Biol. 2007 Jun 1;369(2):584-95. Epub 2007 Mar 24.
PMID: 17434530 [PubMed - indexed for MEDLINE]
- Ribes-Zamora A, Mihalek I, Lichtarge O, Bertuch AA.
Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions.
Nat Struct Mol Biol. 2007 Apr;14(4):301-7. Epub 2007 Mar 11.
PMID: 17351632 [PubMed - indexed for MEDLINE]
- Mihalek I, Res I, Lichtarge O.
Evolutionary trace report_maker: a new type of service for comparative analysis of proteins.
Bioinformatics. 2006 Jul 1;22(13):1656-7. Epub 2006 Apr 27.
PMID: 16644792 [PubMed - indexed for MEDLINE]
- Mihalek I, Res I, Lichtarge O.
A structure and evolution-guided Monte Carlo sequence selection strategy for multiple alignment-based analysis of proteins.
Bioinformatics. 2006 Jan 15;22(2):149-56. Epub 2005 Nov 22.
PMID: 16303797 [PubMed - indexed for MEDLINE]
- Res I, Mihalek I, Lichtarge O.
An evolution based classifier for prediction of protein interfaces without using protein structures.
Bioinformatics. 2005 May 15;21(10):2496-501. Epub 2005 Feb 22.
PMID: 15728113 [PubMed - indexed for MEDLINE]
- Mihalek I, Res I, Yao H, Lichtarge O.
Combining inference from evolution and geometric probability in protein structure evaluation.
J Mol Biol. 2003 Aug 1;331(1):263-79.
PMID: 12875851 [PubMed - indexed for MEDLINE]
- Mihalek I, Res I, Lichtarge O.
A family of evolution-entropy hybrid methods for ranking protein residues by importance.
J Mol Biol. 2004 Mar 5;336(5):1265-82.
PMID: 15037084 [PubMed - indexed for MEDLINE]
|
| |
Please contact us by email if you wish a reprint from any of the selected publications. |
|
|
|
| |
 |
|
