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Dr. Manfred KORANDA
Principal Investigator
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| Group Members |
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| Name | Title |
| Dr. Manfred KORANDA |
Principal Investigator |
| Dr. ADHIKARI Sharmila |
Postdoctoral Fellow |
| Dr. KHOR Hwei Ling |
Postdoctoral Fellow |
| Dr. Krisna PRAK |
Postdoctoral Fellow |
| Ms. TAY Yu Ling Winnie |
Postdoctoral Fellow |
| Mr. LUA Wai Heng |
Research Associate |
| Ms. CHUA Ling Ling |
Research Associate |
| Ms. LIEW Lailing |
Research Associate |
| Ms. Michaela SAMMER |
Research Associate |
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Research Overview
This is a protein biochemistry/molecular biology group involved in the verification of sequence-analytic hypotheses to identify functional regions of proteins and for the generation of experimental data that can be used for the development of new prediction tools. With a set of standardized assays (enzymology, post-translational modifications, identification of protein substrates of enzymes/receptors/ transporters, etc.), our biochemical lab aims to bridge the gap between theoretical predictions on the one hand, and cell biology and genetics research on the other. What is truly unique about the group is our integrated approach. Scientists from multiple disciplines (molecular biology, genetics, biochemistry and bioinformatics) work closely together to fully understand different aspects of the inherently complex systems intrinsic to living organisms.
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| More Details |
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| Selected Publications |
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- Veis J, Klug H, Koranda M, Ammerer G.
Activation of the G2/M-specific gene CLB2 requires multiple cell cycle signals.
Mol Cell Biol. 2007 Dec;27(23):8364-73. Epub 2007 Oct 1.
PMID: 17908798 [PubMed - indexed for MEDLINE]
- Maurer-Stroh S, Koranda M, Benetka W, Schneider G, Sirota FL, Eisenhaber F.
Towards complete sets of farnesylated and geranylgeranylated proteins.
PloS Comput Biol. 2007 Apr 6;3(4):e66. Epub 2007 Feb 23.
PMID: 17411337 [PubMed - indexed for MEDLINE]
- Benetka W, Koranda M, Maurer-Stroh S, Pittner F, Eisenhaber F.
Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo.
BMC Biochem. 2006 Feb 28;7:6.
PMID: 16507103 [PubMed - indexed for MEDLINE]
- Koranda M, Schleiffer A, Endler L, Ammerer G.
Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters.
Nature. 2000 Jul 6;406(6791):94-8.
PMID: 10894549 [PubMed - indexed for MEDLINE]
- Doetzlhofer A, Rotheneder H, Lagger G, Koranda M, Kurtev V, Brosch G, Wintersberger E, Seiser C.
Histone deacetylase 1 can repress transcription by binding to Sp1.
Mol Cell Biol. 1999 Aug;19(8):5504-11.
PMID: 10409740 [PubMed - indexed for MEDLINE]
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